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Article

Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene.

Blood cells, molecules & diseases - 1 Jan 2000

Gordeuk Victor R, Caleffi Angela, Corradini Elena, Ferrara Francesca, Jones Russell A, Castro Oswaldo, Onyekwere Onyinye, Kittles Rick, Pignatti Elisa, Montosi Giuliana, Garuti Cinzia, Gangaidzo Innocent T, Gomo Z A R, Moyo Victor M, Rouault Tracey A, MacPhail Patrick, Pietrangelo Antonello

Abstract excerpt

The product of the SLC40A1 gene, ferroportin 1, is a main iron export protein. Pathogenic mutations in ferroportin 1 lead to an autosomal dominant hereditary iron overload syndrome characterized by high serum ferritin concentration, normal transferrin saturation, iron accumulation predominantly i...

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Source

Identifiers

PMID: 14636642
DOI: 10.1016/s1079-9796(03)00164-5

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14636642-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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