Article
Multiple elements regulate GAD65 transcription.
Developmental neuroscience - 1 Jan 1997
Pinal C S, Cortessis V, Tobin A J
Abstract excerpt
GAD65 and GAD67, the two forms of GABA-synthesizing enzyme, are usually coexpressed, but their levels are regulated independently. The GAD67 promoter has been described. We have now characterized transcriptional regulatory elements in the 5' flanking region of the GAD65 gene, extending 2.4 kb from the ATG translation initiation site. Primer extension assays revealed that transcription begins at -228 in both adult...
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