Article
Persistence and differentiation of HTLV-I-transformed immature T-cells in HTLV-I carrier rabbits.
Leukemia research - 1 Jan 2000
Yoshida H, Nagano Y, Isono T, Seto A
Abstract excerpt
Two T-cell lines with immature phenotypes, CD4-8- and CD4+8+, were found among HTLV-I-transformed T-cell lines obtained during experiments using a rabbit model of adult T-cell leukemia. Persistence and differentiation of these clones in vivo were examined by retrospectively analysing a series of cell lines from individual animals and by adoptive transfer of these cells into syngeneic hosts. The double negative...
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