Article
Pharmacogenetics in biological perspective.
Pharmacological reviews - 1 Dec 1997
Kalow W
Abstract excerpt
What have we learned? Pharmacogenetics, heritable variation in response to xenobiotics, is present in all forms of life. Initially, human data perhaps have created the most excitement, and they provide much biochemical detail. However, if we look at pharmacogenetic variation of insects and bacteria, we see it as a characteristic of populations; individuals with inborn resistance to various toxicants can cause the...
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