Article
Developmental genetics in ophthalmology.
Ophthalmic genetics - 1 Mar 2003
Graw Jochen, Löster Jana
Abstract excerpt
Much of our knowledge about the function of genes in mammalian development has been derived from the molecular analysis of spontaneous or induced mutations in the mouse. Since mutations affecting the mouse eye can be easily identified, a remarkable number of mutant lines provide animal models for congenital anomalies in man. To understand the mechanisms of lens development in detail, the isolation of the...
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