Article
Metazoan nuclear genes for mitoribosomal protein S12.
Gene - 19 Dec 1997
Shah Z H, O'Dell K M, Miller S C, An X, Jacobs H T
Abstract excerpt
We have characterized nuclear genes for mitoribosomal protein S12 (mt-rps12) a major component of the ribosomal accuracy centre, in human, mouse and Drosophila melanogaster. In human and Drosophila, and probably also in mouse, there is a single intron within the coding region, located in the mitochondrial targeting pre-sequence. In humans, the mRNA structure is highly suggestive of translational regulation. In...
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