Article
Renin-angiotensin system gene polymorphisms and left ventricular hypertrophy. The case against an association.
Advances in experimental medicine and biology - 1 Jan 1997
West M J, Summers K M, Wong K K, Burstow D J
Abstract excerpt
There is accumulating evidence for association between genetic polymorphisms of components of the renin angiotensin system (RAS), especially angiotensin-converting enzyme (ACE), and cardiovascular disease. However, there is lack of agreement that the ACE polymorphism is associated with left ventricular hypertrophy (LVH) in hypertension. A possible paradigm for the development of LVH involves the ACE gene...
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