Article
Transcription Repression of Human Hepatitis B Virus Genes by Negative Regulatory Element-binding Protein/SON
1 Jun 2001
Abstract excerpt
A negative regulatory element (NRE) is located immediately upstream of the upstream regulatory sequence of core promoter and second enhancer of human hepatitis B virus (HBV). NRE represses the transcription activation function of the upstream regulatory sequence of core promoter and the second enhancer. In this study, we described the cloning and characterization of an NRE-binding protein (NREBP) through...
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