Article
Overexpression of GML promotes radiation-induced cell cycle arrest and apoptosis.
Biochemical and biophysical research communications - 18 Dec 1997
Kagawa K, Inoue T, Tokino T, Nakamura Y, Akiyama T
Abstract excerpt
Expression of the GML gene is regulated in a p53-dependent manner and is correlated with the sensitivity of esophageal cancer cells to anti-cancer drugs. To clarify the effect of GML expression on the sensitivity of cancer cells to ionizing radiation treatment, we established cell lines derived from p53-mutant human osteosarcoma HOS and esophageal carcinoma TE10 lines in which GML expression can be induced using...
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