Article
Requirement for DCP-1 caspase during Drosophila oogenesis.
Science (New York, N.Y.) - 9 Jan 1998
McCall K, Steller H
Abstract excerpt
Caspases, a class of cysteine proteases, are an essential component of the apoptotic cell death program. During Drosophila oogenesis, nurse cells transfer their cytoplasmic contents to developing oocytes and then die. Loss of function for the dcp-1 gene, which encodes a caspase, caused female sterility by inhibiting this transfer. dcp-1- nurse cells were defective in the cytoskeletal reorganization and nuclear...
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