Article
Germline cell death is inhibited by P-element insertions disrupting the dcp-1/pita nested gene pair in Drosophila.
Genetics - 1 Dec 2003
Laundrie Bonni, Peterson Jeanne S, Baum Jason S, Chang Jeffrey C, Fileppo Dana, Thompson Sharona R, McCall Kimberly
Abstract excerpt
Germline cell death in Drosophila oogenesis is controlled by distinct signals. The death of nurse cells in late oogenesis is developmentally regulated, whereas the death of egg chambers during mid-oogenesis is induced by environmental stress or developmental abnormalities. P-element insertions in the caspase gene dcp-1 disrupt both dcp-1 and the outlying gene, pita, leading to lethality and defective nurse cell...
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