Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system.

doi:10.1128/JVI.72.1.873-875.1998

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Article

Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system.

Journal of virology - 1 Jan 1998

Turner A, Bruun B, Minson T, Browne H

Abstract excerpt

Herpes simplex virus type 1 glycoproteins gB, gD, and gHgL were expressed by transient transfection of Cos cells. Polykaryocyte formation above the background level seen in untransfected controls was observed only if all three components were expressed. Thus, gB, gD, and gHgL are necessary and su...

Topics

Animals
COS Cells
Herpesvirus 1, Human
Membrane Fusion
Mutation
Transfection
Viral Envelope Proteins

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