Three A's of repopulation during fractionated irradiation of squamous epithelia: Asymmetry loss, Acceleration of stem-cell divisions and Abortive divisions

Abstract excerpt

PURPOSE: To analyse the time-course and efficacy of repopulation in squamous epithelia, and to describe possible mechanisms of this regeneration response. MATERIAL AND METHODS: Experimental and clinical studies of repopulation in squamous epithelia have been reviewed to outline general features of repopulation during fractionated radiotherapy. RESULTS: Repopulation processes result in a relative increase in...

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