Article
Citric acid cycle: a mainstream metabolic pathway influencing life span in Drosophila melanogaster?
Experimental gerontology - 1 Jan 2000
Da Cunha G L, de Oliveira A K
Abstract excerpt
The role of the citric acid cycle enzyme NADP-dependent isocitrate dehydrogenase (IDH-NADP) and its allele product variants in resisting the oxidative agent paraquat, was analyzed among descendants of reciprocal crosses between fast developmental time short-lived individuals (F-) and slow developmental time long-lived ones (S+), in Drosophila melanogaster. Taking preadult developmental time into account, the data...
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