Article
A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 1999
van Golen K L, Davies S, Wu Z F, Wang Y, Bucana C D, Root H, Chandrasekharappa S, Strawderman M, Ethier S P, Merajver S D
Abstract excerpt
Inflammatory breast cancer is a rapidly growing, distinct form of locally advanced breast cancer that carries a guarded prognosis. To identify the genes that contribute to this aggressive phenotype, we compared under- and overexpressed sequences in an inflammatory breast tumor cell line with those of actively replicating normal human mammary epithelial cell lines using differential display. Of the 17 transcripts...
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