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Article

Correlation between p53 status, DNA ploidy, proliferation rate and nuclear morphology in breast cancer. An image cytometric study.

Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology - 1 Jan 1997

Friedrich K, Dimmer V, Haroske G, Meyer W, Theissig F, Kunze K D

Abstract excerpt

The study was designed to detect differences in the nuclear morphology of tumours and tumour cell populations with different p53 expression in correlation with DNA ploidy and proliferation rate. The paraffin sections from routinely processed samples of 88 breast cancers were immunostained with the monoclonal p53-antibody DO-1. After localization and evaluation with a scoring system the sections were destained and...

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Identifiers

PMID: 9413594
DOI: 10.1155/1997/719876
PMCID: PMC4611165

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