Article
Correlation between p53 status, DNA ploidy, proliferation rate and nuclear morphology in breast cancer. An image cytometric study.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology - 1 Jan 1997
Friedrich K, Dimmer V, Haroske G, Meyer W, Theissig F, Kunze K D
Abstract excerpt
The study was designed to detect differences in the nuclear morphology of tumours and tumour cell populations with different p53 expression in correlation with DNA ploidy and proliferation rate. The paraffin sections from routinely processed samples of 88 breast cancers were immunostained with th...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal
- Breast Neoplasms
- Cell Division
- Cell Nucleus
- Genes, p53
- Humans
- Immunohistochemistry
- Middle Aged
- Mutation
- Ploidies
- Tumor Suppressor Protein p53