Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species.

doi:10.1016/s0009-2797(97)00068-9

Back to search

Article

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species.

Chemico-biological interactions - 24 Oct 1997

Guengerich F P

Abstract excerpt

Historically there has been considerable interest in comparing patterns of biotransformation of xenobiotic chemicals in experimental animal models and humans, e.g. in areas such as drug metabolism and chemical carcinogenesis. With the availability of more basic knowledge it has become possible to...

Topics

Alleles
Animals
Catalysis
Cytochrome P-450 Enzyme System
Humans
Mutagenesis, Site-Directed
Polymorphism, Genetic
Species Specificity

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.