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Article

Radioactive iodine induces clastogenic and age-dependent aneugenic effects in lymphocytes of thyroid cancer patients as revealed by interphase FISH.

Mutagenesis - 1 Nov 1997

Ramírez M J, Surrallés J, Galofré P, Creus A, Marcos R

Abstract excerpt

After the Chernobyl nuclear accident, a dramatic 131I-related increase in the incidence of thyroid cancer has been reported in exposed children. However, little is known about the eventual genotoxic effects of 131I in exposed humans. Thyroid cancer patients are usually treated with 131I and, ther...

Topics

Adolescent
Adult
Age Factors
Aged
Aneuploidy
Cells, Cultured
Centromere
Child
Female
Humans
In Situ Hybridization, Fluorescence
Interphase
Iodine Radioisotopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes

Micronuclei, Chromosome-Defective

Middle Aged

Mutation

Nondisjunction, Genetic

Source

Identifiers

PMID: 9412999
DOI: 10.1093/mutage/12.6.449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9412999-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Radioactive iodine induces clastogenic and age-dependent aneugenic effects in lymphocytes of thyroid cancer patients as revealed by interphase FISH.PMID 9412999Read ↗

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