Article
Prospective study of apolipoprotein E genotype and functional outcome following ischemic stroke.
Archives of neurology - 1 Oct 2000
McCarron M O, Muir K W, Nicoll J A, Stewart J, Currie Y, Brown K, Bone I
Abstract excerpt
BACKGROUND: The apolipoprotein E (APOE) epsilon 4 allele is a marker of adverse outcome following head injury and intracerebral hemorrhage. Transgenic animal data in a focal cerebral ischemia model suggest that the epsilon 4 allele increases infarct size and functional impairment. OBJECTIVE: To determine if APOE genotype is associated with functional recovery from ischemic stroke. DESIGN: Prospective study....
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