Article
B cells and monocytes are not developmentally affected in a case of reticular dysgenesis.
Clinical and experimental immunology - 1 Dec 1997
De La Calle-Martín O, Badell I, García A, Gelpí C, Casamitjana N, Estella J, Rodríguez-Sánchez J L
Abstract excerpt
We report a patient with reticular dysgenesis (RD) who received an HLA-identical marrow graft and remained free of infection in spite of incomplete haematological recovery. Mixed chimerism was achieved and resulted from the presence of autologous B cells and monocytes and grafting of donor T cells. Granulocyte recovery was impaired. The B cells were CD5+ (B1 cells) and appeared to be functional, since serum...
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