Article
Liver LDL receptor mRNA expression is decreased in human ApoB/CETP double transgenic mice and is regulated by diet as well as the cytokine oncostatin M.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1997
Liu J, Zhang Y L, Spence M J, Vestal R E, Wallace P M, Grass D S
Abstract excerpt
We have investigated liver LDL receptor mRNA expression in nontransgenic, human cholesteryl ester transfer protein (CETP) transgenic, and human apolipoprotein (Apo) B/CETP double transgenic mice fed a normal chow diet and a high fat, high cholesterol diet (HFHC). Three weeks of HFHC feeding increased total serum cholesterol 1.5-fold in the nontransgenic, 3.1-fold in the CETP transgenic, and 3.4-fold in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
