Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel BRCA1 mutation in an identical twin pair with similar clinical histories.

Cancer genetics and cytogenetics - 1 Jan 1998

Miesfeldt S, Turner B L, Lovell M A, Cooper M R, Lescallett J, Jones S M

Abstract excerpt

Factors affecting the penetrance and expression of BRCA1 are not understood. Breast cancer risk and ovarian cancer risk, in general, are known to be associated with non-Mendelian factors. However, whether and how these various factors influence tumor development in BRCA1 mutation carriers is not known. Here we report the breast and ovarian cancer syndrome in an identical twin pair. These female identical twins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Diseases in Twins
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Mutation

Share to Ovarian Neoplasms

Share to Twins, Monozygotic

Source

Identifiers

PMID: 9406579
DOI: 10.1016/s0165-4608(97)00006-x

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel BRCA1 mutation in an identical twin pair with similar clinical histories.PMID 9406579Read ↗

Caucasian family with two independent mutations: 2594delC in BRCA1 and 5392delAG in BRCA2 gene.Semantic proximity Read ↗

Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer.Semantic proximity Read ↗

Novel BRCA1 deleterious mutation (c.1918C>T) in familial breast and ovarian cancer syndrome who share a common ancestry.Semantic proximity Read ↗

BRCA1 R841W: a strong candidate for a common mutation with moderate phenotype.Semantic proximity Read ↗

BRCA1-related and sporadic ovarian cancer in the same family: implications for genetic testing.Semantic proximity Read ↗

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.Semantic proximity Read ↗

The genetic causes of the sequential occurrence of multiple primary malignancies in a young woman--5 years on.Semantic proximity Read ↗

[Breast cancer in monozygotic twins].Semantic proximity Read ↗

Functional Characterization of a Novel BRCA1-Null Ovarian Cancer Cell Line in Response to Ionizing RadiationSemantic proximity Read ↗

A large kindred with 17q-linked breast and ovarian cancer: genetic, phenotypic, and genealogical analysis.Semantic proximity Read ↗

The founder mutation BRCA1c.2845insA identified in a fallopian tube cancer patient: a case report.Semantic proximity Read ↗

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.