Article
Transcription regulation by initiating NTP concentration: rRNA synthesis in bacteria.
Science (New York, N.Y.) - 19 Dec 1997
Gaal T, Bartlett M S, Ross W, Turnbough C L, Gourse R L
Abstract excerpt
The sequence of a promoter determines not only the efficiency with which it forms a complex with RNA polymerase, but also the concentration of nucleoside triphosphate (NTP) required for initiating transcription. Escherichia coli ribosomal RNA (rrn P1) promoters require high initiating NTP concentrations for efficient transcription because they form unusually short-lived complexes with RNA polymerase; high...
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