Article
Mutations at the lipoprotein lipase gene locus in subjects with diabetes mellitus, obesity and lipaemia.
Clinical science (London, England : 1979) - 1 Oct 1997
Zhang Q, Cavallero E, Hoffmann M M, Cavanna J, Kay A, Charles A, Braschi S, Marz W, Perlemuter L, Jacotot B, Galton D J
Abstract excerpt
1. The common association of obesity, diabetes mellitus and hyperlipidaemia may have a primary aetiological basis. Insulin resistance has been postulated as a possible cause, but defects in the plasma transport of triacylglycerol or fatty acids could also be primary determinants. 2. We have there...
Topics
- Adult
- Aged
- Alleles
- Autoradiography
- Diabetes Mellitus
- Exons
- Female
- Humans
- Hypertriglyceridemia
- Lipoprotein Lipase
- Male
- Middle Aged
- Mutagenesis, Site-Directed
- Mutation
- Obesity
- Sequence Analysis, DNA