Article
Lipoprotein lipase activity and common gene variants in severely hypertriglyceridemic patients with and without diabetes.
Hormone research - 1 Jan 2003
Chadarevian Rita, Foubert Luc, Beucler Isabel, Kottler Marie-Laure, Raisonnier Alain, Ajlouni Ali, Giral Philippe, Turpin Gérard, Bruckert Eric
Abstract excerpt
OBJECTIVES: In severe type IV hypertriglyceridemia (triglyceride levels >10 g/l), it is yet unknown whether lipoprotein lipase (LPL) differs according to the presence or not of diabetes. METHODS: We compared LPL activity and the presence of four common variants in the LPL gene (Asp 9 Asn (exon 2), Gly 188 Glu (exon 5), Asn 291 Ser (exon 6) and Ser 447 Ter (exon 9)) in a group of 34 patients of whom 17 presented...
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