Article
Genetic predisposition to hyperlipidaemia in diabetes: the end of the beginning?
Journal of internal medicine. Supplement - 1 Jan 1994
Wilson D E, Kwong L K, Elbein S C, Lalouel J M
Abstract excerpt
Diabetes mellitus leads to disturbances in lipoprotein homeostasis particularly when there is poor glycaemic control. The resulting abnormalities in concentration and composition of the circulating lipoproteins are modified by inherited variation in the genes coding for apolipoproteins, for the lipoprotein-processing enzymes, and possibly for lipoprotein receptors. Thus, poorly controlled diabetes provides an...
Topics
- Alleles
- Apolipoproteins
- Diabetes Mellitus
- Female
- Genotype
- Humans
- Hyperlipidemias
- Lipoprotein Lipase
- Male
- Mutation
- Pedigree
- Polymorphism, Genetic
