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Article

Phenotypic correction of Age-associated functional decline in murine immune cells by Thymax, a thymic extract.

In vivo (Athens, Greece) - 1 Jan 2000

Ghoneum Mamdooh, Tolentino Lucilene, Seto Yoshikazu

Abstract excerpt

BACKGROUND: We have recently demonstrated that Thymax, a gross thymic extract, induces the functional activity of human dendritic cells (DCs) in vitro. In this study, the role of Thymax in phenotypic correction of age-associated functional decline in immune cells in mice was evaluated. MATERIALS AND METHODS: C57BL/6 mice (13 months old) were treated with Thymax orally (20% v/v) for 4 weeks. Different splenic cell...

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PMID: 20023230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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