[The biological activity of chalone-like proteoglycans isolated from the spleen and thymus at various periods of ontogeny].

Article

[The biological activity of chalone-like proteoglycans isolated from the spleen and thymus at various periods of ontogeny].

Ontogenez - 1 Jan 2000

Ronichevskaia G M, Smirnov P N, Goncharova N B, Zlobina G A

Abstract excerpt

Chalone-like proteoglycans from sheep and bovine thymus and spleen were shown to suppress cell proliferation in murine thymus or spleen. Their effect appeared to be organ-specific but not species-specific. Administration of the proteoglycans resulted in a decrease in the mitotic activity of thymu...

Topics

Aging
Animals
Antineoplastic Agents
Cattle
Genotype
Growth Inhibitors
Lymphocytes
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mitosis
Proteoglycans
Sheep
Spleen
Thymus Gland

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