Article
Inflammatory bowel disease aggregation in Utah kindreds.
Inflammatory bowel diseases - 1 Mar 2011
Guthery Stephen L, Mineau Geraldine, Pimentel Richard, Williams Marc S, Kerber Richard A
Abstract excerpt
BACKGROUND: The observed heritability of inflammatory bowel disease (IBD) is incompletely explained by known genetic risk factors. Kindred-specific genetic variants that cause IBD may be a source of "missing heritability." Given that they have been previously difficult to identify, we sought to identify high-risk IBD kindreds. METHODS: We used a large population-based database--the Utah Population Database...
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