The role of estrogen receptor mutations in tamoxifen-stimulated breast cancer.

doi:10.1016/s0960-0760(97)00034-4

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Article

The role of estrogen receptor mutations in tamoxifen-stimulated breast cancer.

The Journal of steroid biochemistry and molecular biology - 1 Jun 1997

Tonetti D A, Jordan V C

Abstract excerpt

During the past 20 years, the hormonal therapy of choice for the treatment of breast cancer has been the antiestrogen, tamoxifen. The use of tamoxifen has been proved to produce a favorable response and survival advantage in patients whose tumors are classified as estrogen receptor-positive (ER+)...

Topics

Antineoplastic Agents, Hormonal
Breast Neoplasms
Drug Resistance, Neoplasm
Female
Humans
Mutation
Receptors, Estrogen
Tamoxifen

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