Article
Phenotyping of the glutathione S-transferase M1 polymorphism in Zimbabweans and the effects of chloroquine on blood glutathione S-transferases M1 and A.
Clinica chimica acta; international journal of clinical chemistry - 30 Sept 1997
Mukanganyama S, Masimirembwa C M, Naik Y S, Hasler J A
Abstract excerpt
The frequency of the null allele phenotype of glutathione S-transferase (GST) M1 was investigated in 114 Zimbabweans and results for a subset of 63 subjects were compared with genotyping by PCR. In addition, the effect of the antimalarial chloroquine on blood levels of GSTM1 and GSTA in 19 subjec...
Topics
- Antimalarials
- Chloroquine
- Enzyme-Linked Immunosorbent Assay
- Glutathione Transferase
- Humans
- Isoenzymes
- Male
- Phenotype
- Polymorphism, Genetic