Article
Codon-usage variants in the polymorphic (GGN)n trinucleotide repeat of the human androgen receptor gene.
Human genetics - 1 Nov 1997
Lumbroso R, Beitel L K, Vasiliou D M, Trifiro M A, Pinsky L
Abstract excerpt
The human androgen receptor gene (hAR) has a long, polymorphic trinucleotide (GGN; glycine)n repeat in the 3' portion of its first exon, with n = 10-31. Owing to technical difficulties that have precluded routine sequencing of this region, it is widely unknown that N represents T, G or C, and that the usual sense codon sequence of the GGN tract is (GGT)3GGG(GGT)2(GGC)4-25. Furthermore, on 4 of 61 X chromosomes,...
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