Article
Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis.
Structure (London, England : 1993) - 15 Nov 1997
Al-Karadaghi S, Hansson M, Nikonov S, Jönsson B, Hederstedt L
Abstract excerpt
BACKGROUND: The metallation of closed ring tetrapyrroles resulting in the formation of hemes, chlorophylls and vitamin B12 is catalyzed by specific enzymes called chelatases. Ferrochelatase catalyzes the terminal step in heme biosynthesis by inserting ferrous ion into protoporphyrin IX by a mecha...
Topics
- Amino Acid Sequence
- Bacillus subtilis
- Binding Sites
- Conserved Sequence
- Crystallography, X-Ray
- Ferrochelatase
- Metals
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Porphyrins
- Protein Conformation
- Protoporphyrins