Article
Binary specification of the embryonic lineage in Caenorhabditis elegans.
Nature - 20 Nov 1997
Kaletta T, Schnabel H, Schnabel R
Abstract excerpt
In Caenorhabditis elegans, the early embryo contains five somatic founder cells (known as AB, MS, E, C and D) which give rise to very different lineages. Two simply produce twenty intestinal (E) or muscle (D) cells each, whereas the remainder produce a total of 518 cells which collectively contribute in a complex pattern to a variety of tissues. A central problem in embryonic development is to understand how the...
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