Article
Autosomal dominant dementia with widespread neurofibrillary tangles.
Annals of neurology - 1 Oct 1997
Reed L A, Grabowski T J, Schmidt M L, Morris J C, Goate A, Solodkin A, Van Hoesen G W, Schelper R L, Talbot C J, Wragg M A, Trojanowski J Q
Abstract excerpt
Several familial dementing conditions with atypical features have been characterized, but only rarely is the neuropathology dominated solely by neurofibrillary lesions. We present a Midwestern American pedigree spanning four generations in which 15 individuals were affected by early-onset dementi...
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