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PSEN2 Mutations May Mimic Frontotemporal Dementia: Two New Case Reports and a Systematic Review

2024-07-30

Abstract excerpt

<h4>Background: </h4> Monogenic Alzheimer's disease (AD) has severe health and socioeconomic repercussions. Its rarest cause are presenilin 2 (PSEN2) gene mutations. We present two new cases with presumed PSEN2-AD, with unusual clinical and neuroimaging findings in order to provide more information on the pathophysiology and semiology of these patients. <h4>Methods:</h4> Women aged 69 and 62 years at clinical...

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Literature Corpus work: cef0d809-25d5-58fc-959e-f2913369243c
DOI: 10.20944/preprints202407.2466.v1

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