Article
The Saccharomyces cerevisiae ACR3 gene encodes a putative membrane protein involved in arsenite transport.
The Journal of biological chemistry - 28 Nov 1997
Wysocki R, Bobrowicz P, Ułaszewski S
Abstract excerpt
The cluster of three genes, ACR1, ACR2, and ACR3, previously was shown to confer arsenical resistance in Saccharomyces cerevisiae. The overexpression of ACR3 induced high level arsenite resistance. The presence of ACR3 together with ACR2 on a multicopy plasmid was conducive to increased arsenate resistance. The function of ACR3 gene has now been investigated. Amino acid sequence analysis of Acr3p showed that this...
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