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Article

Multiple myeloma with t(11;14)-associated immature phenotype has lower CD38 expression and higher BCL2 dependence.

Cancer science - 1 Sept 2021

Kitadate Akihiro, Terao Toshiki, Narita Kentaro, Ikeda Sho, Takahashi Yuto, Tsushima Takafumi, Miura Daisuke, Takeuchi Masami, Takahashi Naoto, Matsue Kosei

Abstract excerpt

CD38 expression on myeloma cells is a critical factor affecting the early response to the anti-CD38 antibody daratumumab. However, factors affecting CD38 expression in untreated multiple myeloma are not fully elucidated. In this study, we found that CD38 expression was significantly lower in myeloma patients with the translocation t(11;14)-associated immature plasma cell phenotype, and particularly in those...

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Identifiers

PMID: 34288263
DOI: 10.1111/cas.15073
PMCID: PMC8409299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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