Article
Progressive myeloma after thalidomide therapy in a patient with immature phenotype of myeloma (plasma) cells.
International journal of hematology - 1 May 2004
Okikawa Yoshiko, Sakai Akira, Takimoto Yasuo, Noda Masaaki, Imagawa Jun, Katayama Yuta, Kuroda Yoshiaki, Okita Hajime, Fujimura Kingo, Kimura Akiro
Abstract excerpt
In our experience with thalidomide treatment for refractory multiple myeloma (MM), most patients with progressive disease (PD) did not show an increase in M-protein despite the tumor burden of myeloma cells. This finding led us to suspect that proliferation of immature myeloma cells showing MPC-1(-)/CD49e(-) phenotype may be a sign of PD. We report the results of consecutive analysis of the phenotype of myeloma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
