Article
HLA class II genes in soybean epidemic asthma patients.
American journal of respiratory and critical care medicine - 1 Nov 1997
Soriano J B, Ercilla G, Sunyer J, Real F X, Lázaro C, Rodrigo M J, Estivill X, Roca J, Rodríguez-Roisín R, Morell F, Antó J M
Abstract excerpt
From 1981 to 1987, 26 outbreaks of asthma caused by the inhalation of soybean dust, affecting a total of 688 individuals, were detected in Barcelona, Spain. Because only a small proportion of asthmatic individuals living in Barcelona expressed the epidemic phenotype, it is hypothesized that a genetically determined human leukocyte antigen (HLA) Class II factor could have played a role in the susceptible...
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