Article
A splice variant of Dp71 lacking the syntrophin binding site is expressed in early stages of human neural development.
Brain research. Developmental brain research - 20 Oct 1997
Ceccarini M, Rizzo G, Rosa G, Chelucci C, Macioce P, Petrucci T C
Abstract excerpt
Dp71, a 71 kDa C-terminal isoform of dystrophin, is the major product of the DMD gene in brain. Two alternatively spliced transcripts of Dp71 were amplified by RT-PCR from different areas of human fetal neural tissue. Both transcripts were spliced out of exons 71 and 78. The shorter transcript was also alternatively spliced of exons 72-74, a region comprising the coding sequence for the binding site to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.