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Article

ICP0 Gene Expression Is a Herpes Simplex Virus Type 1 Apoptotic Trigger

29 Jun 2006

Abstract excerpt

Apoptosis is a highly regulated programmed cell death process which is activated during normal development and by various stimuli, such as viral infection, which disturb cellular metabolism and physiology. That herpes simplex virus type 1 (HSV-1) induces apoptosis but then prevents its killing of infected cells is well-established. However, little is known about the viral factor/event which triggers the apoptotic...

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PMID: 16809287
DOI: 10.1128/jvi.00334-06

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