Article
Eotaxin influences the development of embryonic hematopoietic progenitors in the mouse.
Journal of leukocyte biology - 1 Nov 1997
Quackenbush E J, Aguirre V, Wershil B K, Gutierrez-Ramos J C
Abstract excerpt
Eotaxin is a potent chemoattractant for eosinophils during inflammation and allergic reactions in the adult, but its role during development has not been studied. We report that eotaxin and its receptor, CCR-3, are expressed by embryonic tissues responsible for blood development, including the yolk sac, fetal liver, and fetal blood. We also found that eotaxin acts synergistically with stem cell factor (SCF) to...
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