Alloresponses to HLA-DP detected in the primary MLR: correlation with a single amino acid difference.

doi:10.1016/s0198-8859(97)00091-8

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Article

Alloresponses to HLA-DP detected in the primary MLR: correlation with a single amino acid difference.

Human immunology - 1 Jul 1997

Nicholson I, Varney M, Kanaan C, Grigg A, Szer J, Tiedemann K, Tait B D

Abstract excerpt

The one-way mixed lymphocyte reaction (MLR-1) response was measured in both directions in 50 HLA-A, B, DR and DQ identical pairs and the role of DP studied in MLR stimulation. DR, DQ and DP typing was performed at the allele level by the polymerase chain reaction-sequence specific oligotyping (PC...

Topics

Alleles
Animals
Graft vs Host Disease
HLA-DP Antigens
HLA-DP beta-Chains
Humans
Lymphocyte Activation
Lymphocyte Culture Test, Mixed
Rabbits
Structure-Activity Relationship
T-Lymphocytes

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