Article
A two-stage half-sib design for mapping quantitative trait loci in food animals.
Journal of dairy science - 1 Oct 1997
Du F X, Woodward B W
Abstract excerpt
Daughter and granddaughter half-sib designs for mapping quantitative trait loci were modified to increase experimental power. This new design includes a two-stage procedure, in contrast to conventional one-step half-sib designs. In stage 1, a few progeny of each sire are genotyped for marker loci. Based on the analyses of stage 1 data, some sires are chosen to continue genotyping more progeny for stage 2. When...
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