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Article

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line.

Nature medicine - 1 Nov 1997

Bedwell D M, Kaenjak A, Benos D J, Bebok Z, Bubien J K, Hong J, Tousson A, Clancy J P, Sorscher E J

Abstract excerpt

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) protein. While 70% of CF chromosomes carry a deletion of the phenylalanine residue 508 (deltaF508) of CFTR, roughly 5% of all CF chromosomes carry a premature stop mutation. We reported that the amino...

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PMID: 9359706
DOI: 10.1038/nm1197-1280

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CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9359706-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line.PMID 9359706Read ↗

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Pharmacological Responses of the G542X-CFTR to CFTR ModulatorsSemantic proximity Read ↗

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