Article
HLA DRB1* and DQB1* alleles are associated with disease severity in patients with pemphigus vulgaris.
International journal of dermatology - 1 Feb 2015
Svecova Danka, Parnicka Zuzana, Pastyrikova Lucia, Urbancek Slavomir, Luha Jan, Buc Milan
Abstract excerpt
BACKGROUND: Pemphigus vulgaris (PV) is a rare autoimmune disease that involves the skin and mucosa. The etiology of PV is multifactorial and includes genetic, environmental, hormonal, and immunological factors. OBJECTIVES: The purpose of this study was to examine the relationships between human leukocyte antigen (HLA) class II alleles associated with PV and variations in the disease phenotype. METHODS: Forty-four...
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