Article
The prognostic potential of bone marrow cyclin E and P27, in Egyptian patients with acute myeloid leukemia.
The Egyptian journal of immunology - 1 Jan 2010
Abdel Alim Afaf, Youssef Soha R, Farouk Hanan Mohamed
Abstract excerpt
Cyclin E and the cyclin dependent kinase inhibitor P27 are two important regulators of the G1-S transition modulating the activity of cyclin-dependent kinases. Aberrations in the cell cycle control are often observed in tumors and might even be mandatory in tumor development. There are few molecular biologic determinants that may be prognostic for patients with acute myeloid leukemia (AML). To investigate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.