Article
Mutational analysis of human T-cell leukemia virus type 2 Tax.
Journal of virology - 1 Nov 1997
Ross T M, Minella A C, Fang Z Y, Pettiford S M, Green P L
Abstract excerpt
A mutational analysis of human T-cell leukemia virus type 2 (HTLV-2) Tax (Tax-2) was performed to identify regions within Tax-2 important for activation of promoters through the CREB/ATF or NF-kappaB/Rel signaling pathway. Tax-2 mutations within the putative zinc-binding region as well as mutatio...
Topics
- Amino Acid Sequence
- Animals
- COS Cells
- Cell Compartmentation
- Cell Line
- Cell Nucleus
- Gene Expression Regulation, Viral
- Gene Products, tax
- Genes, Viral
- Human T-lymphotropic virus 1
- Human T-lymphotropic virus 2
- Humans
- Molecular Sequence Data
- NF-kappa B
- Nuclear Proteins
- Phenotype
- Promoter Regions, Genetic
- Sequence Alignment