Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Permeability to carbapenems of Proteus mirabilis mutants selected for resistance to imipenem or other beta-lactams.

The Journal of antimicrobial chemotherapy - 1 Sept 1997

Villar H E, Danel F, Livermore D M

Abstract excerpt

An imipenem-resistant mutant of Proteus mirabilis lacked a 26 kDa outer membrane protein (OMP). It has previously been postulated that this protein is a porin, but the present mutant, which was cross-resistant to mecillinam but not to other beta-lactams, proved as permeable to carbapenems as its...

Topics

Amdinocillin
Anti-Bacterial Agents
Bacterial Outer Membrane Proteins
Carbapenems
Cefoxitin
Cell Membrane Permeability
Imipenem
Mutation
Proteus mirabilis
beta-Lactam Resistance
beta-Lactamases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9338488
DOI: 10.1093/jac/40.3.365

Genes

OMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9338488-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Permeability to carbapenems of Proteus mirabilis mutants selected for resistance to imipenem or other beta-lactams.PMID 9338488Read ↗

Imipenem- and meropenem-resistant mutants of Enterobacter cloacae and Proteus rettgeri lack porins.Semantic proximity Read ↗

Loss of a 29-kilodalton outer membrane protein in Acinetobacter baumannii is associated with imipenem resistance.Semantic proximity Read ↗

Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa.Semantic proximity Read ↗

Decreased permeability and enhanced proton-dependent active efflux in the development of resistance to quinolones in Morganella morganii.Semantic proximity Read ↗

Genetics of Acquired Antibiotic Resistance Genes in Proteus spp.Semantic proximity Read ↗

Evolution of β-Lactam Antibiotic Resistance in Proteus Species: From Extended-Spectrum and Plasmid-Mediated AmpC β-Lactamases to CarbapenemasesSemantic proximity Read ↗

Diversity of TEM mutants in Proteus mirabilis.Semantic proximity Read ↗

Evolution of β-Lactam Antibiotic Resistance in <i>Proteus</i> Species: From Extended-Spectrum and Plasmid-Mediated AmpC β-Lactamases to CarbapenemasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.